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Merck
CN

700119P

Avanti

7α,24(R/S)-dihydroxycholesterol-d7

Avanti Research - A Croda Brand

Synonym(s):

111113

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About This Item

Empirical Formula (Hill Notation):
C27H39D7O3
CAS Number:
Molecular Weight:
425.70
MDL number:
UNSPSC Code:
41141804
NACRES:
NA.25
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Product Name

7α,24(R/S)-dihydroxycholesterol-d7, 7α,24(R/S)-dihydroxycholesterol-d7, powder

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700119P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 700119P

shipped in

dry ice

storage temp.

−20°C

General description

7α,24(R/S)-dihydroxycholesterol-d7 is a deuterated derivative of 7α,24(R/S)-dihydroxycholesterol and is a oxysterol.

Biochem/physiol Actions

7α,24(R/S)-dihydroxycholesterol is a racemic mixture. 7α,24(S)-dihydroxycholesterol (7α,24(S)-diOHC) is synthesized from 24(S)-OHC in the presence of enzyme oxysterol 7-α-hydroxylase 2 (CYP39A1). 7α,24(S)-diOHC is a ligand for liver X receptor (LXR).

Packaging

5 mL Amber Glass Screw Cap Vial (700119P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available


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Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
Guillemot-Legris O, et al.
Scientific Reports null
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters null

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