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About This Item
Empirical Formula (Hill Notation):
C45H71D7O2
CAS Number:
Molecular Weight:
658.14
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
18:1 Chol (D7) ester, 25,26,26,26,27,27,27-heptadeuteriocholest-5-en-3β-ol (9Z-octadecenoate), methylene chloride solution
assay
>99% (TLC)
form
methylene chloride solution
packaging
pkg of 1 × 1 mL (700185M-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700185M
concentration
1 mg/mL (700185M-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
18:1 Chol (D7) ester is a deuterated derivative of cholesteryl oleate (18:1 Cholester). 18:1 Chol (D7) ester is a component of Splash™LipidoMix™ standard from Avanti and is used as an internal standard in ultrahigh performance liquid chromatography (UHPLC)-mass spectrometry (MS) analysis for profiling cerebrospinal fluid lipids.
Biochem/physiol Actions
Cholesteryl oleate (18:1 Cholester) association with low-density lipoproteins (LDL) promotes atherosclerosis. The diet comprising monounsaturated fatty acids promotes cholesteryl ester secretion and association with lipoproteins.
Packaging
5 mL Clear Glass Sealed Ampule (700185M-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Central nervous system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
Regulatory Information
危险化学品
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Ane Iriondo et al.
Talanta, 195, 619-627 (2019-01-11)
The cerebrospinal fluid (CSF) lipidome is attracting increasing attention due to the importance of lipids in brain molecular signaling and their involvement in several neurological diseases. Different solvent systems have been used for the extraction of multiple lipid classes from
Chiara Degirolamo et al.
Journal of lipid research, 50 Suppl, S434-S439 (2008-11-26)
This review focuses on the relationships among dietary fat type, plasma and liver lipid, and lipoprotein metabolism and atherosclerosis. Dietary polyunsaturated fatty acids are beneficial for the prevention of coronary artery atherosclerosis. By contrast, dietary monounsaturated fatty acids appear to
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