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Merck
CN

790625C

Avanti

DC-Chol/DOPE Blend

Avanti Research™ - A Croda Brand

Synonym(s):

DC-Chol/DOPE Blend, DC-Cholesterol/Dioleoyl Phosphatidylethanolamine (30:70, w/w)

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

DC-Chol/DOPE Blend, Avanti Research™ - A Croda Brand 790625C

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (790625C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 790625C

concentration

10 mg/mL (790625C-25mg)

lipid type

cationic lipids

shipped in

dry ice

storage temp.

−20°C

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General description

DC-Chol/DOPE blend is a cationic lipid blend.
DC-Chol/DOPE is a blend of a cationic lipid : 3b-[N-(N′, N′ dimethyl-aminoethane)carbomyl] (DC-Chol ) and a neutral lipid : dioleoyl phosphatidylethanolamine (DOPE).

Biochem/physiol Actions

The DC-Chol/DOPE blend is widely useful in liposome preparation as it influences the process of encapsulation. 1:2 or 3:2 is a preferred molar ratio for DC-Chol/DOPE liposomes.

Packaging

5 mL Clear Glass Sealed Ampule (790625C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品
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Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease
Leone P, et al.
Annals of Neurology, 48(1), 27-38 (2000)
Shuoye Yang et al.
International journal of pharmaceutics, 434(1-2), 155-160 (2012-05-31)
Three most commonly used preparative methods, dry-film, reverse phase evaporation and ethanol injection were employed to prepare cationic liposomes composed of DC-Chol and DOPE, respectively. The resulting samples were contrasted through morphology observation, particle size and zeta potential analysis. Sephadex

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