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About This Item
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
DC-Chol/DOPE Blend, Avanti Research™ - A Croda Brand 790625C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (790625C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 790625C
concentration
10 mg/mL (790625C-25mg)
lipid type
cationic lipids
shipped in
dry ice
storage temp.
−20°C
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General description
DC-Chol/DOPE blend is a cationic lipid blend.
DC-Chol/DOPE is a blend of a cationic lipid : 3b-[N-(N′, N′ dimethyl-aminoethane)carbomyl] (DC-Chol ) and a neutral lipid : dioleoyl phosphatidylethanolamine (DOPE).
Biochem/physiol Actions
The DC-Chol/DOPE blend is widely useful in liposome preparation as it influences the process of encapsulation. 1:2 or 3:2 is a preferred molar ratio for DC-Chol/DOPE liposomes.
Packaging
5 mL Clear Glass Sealed Ampule (790625C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system
WGK
WGK 3
Regulatory Information
易制毒化学品（2类）
危险化学品
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Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease
Leone P, et al.
Annals of Neurology, 48(1), 27-38 (2000)
Shuoye Yang et al.
International journal of pharmaceutics, 434(1-2), 155-160 (2012-05-31)
Three most commonly used preparative methods, dry-film, reverse phase evaporation and ethanol injection were employed to prepare cationic liposomes composed of DC-Chol and DOPE, respectively. The resulting samples were contrasted through morphology observation, particle size and zeta potential analysis. Sephadex
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