793024P
Avanti
DMG-PEG2000-Maleimide
Avanti Research™ - A Croda Brand
Synonym(s):
1,2-dimyristoyl-rac-glycero-3 -[maleimide (polyethylene glycol)-2000]
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About This Item
Empirical Formula (Hill Notation):
C42H74N2O9
Molecular Weight:
751.04
UNSPSC Code:
12352211
biological source
synthetic
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (793024P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
polymerizable lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCC(=O)OCC(COCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCC
Related Categories
General description
DMG-PEG-2000-Maleimide, is a lipid excipient designed for the preparation of lipid nanoparticles (LNPs) for RNA delivery. It is derived from dimyristoyl glycerol (DMG) and exhibits similar properties as phospholipids in the way it associates with membranes.
Features and Benefits
The maleimide group reacts with thiol groups on peptides, enabling the conjugation of bioactive molecules to the surface of lipid nanoparticles. This distinctive property allows the design of LNPs specifically engineered for targeted delivery to particular cell types.
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Regulatory Information
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