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About This Item
Empirical Formula (Hill Notation):
C42H74N5O11P
CAS Number:
Molecular Weight:
856.04
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
16:0-12:0 NBD PC, Avanti Research™ - A Croda Brand 810131C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810131C-1mg)
pkg of 5 × 1 mL (810131C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810131C
concentration
1 mg/mL (810131C-1mg)
1 mg/mL (810131C-5mg)
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) is a common phospholipid found in eukaryotes and a prime metabolite of glycerolipid metabolism. It is a vital component of the mucosal layer of the colon. NBD PC is a fluorescently labeled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to phosphatidylcholine.
Application
16:0-12:0 NBD PC has been used as a fluorescent marker to study the adsorption of hyaluronan (HA) onto a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayer deposited on a silica surface by fluorescent microscopy. It may also be used:
- in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes
- as a fluorophore for DPPC in fluorescence recovery experiments
- as a substrate to test scramblase activity
Biochem/physiol Actions
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is useful in the study of cellular processes as it functions as a fluorescent analog in lipid membranes and phospholipid phase transitions.
Packaging
5 mL Amber Glass Screw Cap Vial (810131C-1mg)
5 mL Amber Glass Screw Cap Vial (810131C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
危险化学品
易制毒化学品（2类）
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The diffusion law of DMPC and DPPC in Supported Lipid Bilayers (SLB), on different substrates, has been investigated in details by Fluorescence Recovery After Patterned Photobleaching (FRAPP). Over micrometer length scales, we demonstrate the validity of a purely Brownian diffusive
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Analytical ultracentrifugation is a widely used method for characterizing the solution behavior of macromolecules. However, the two commonly used detectors, absorbance and interference, impose some fundamental restrictions on the concentrations and complexity of the solutions that can be analyzed. The
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