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About This Item
Empirical Formula (Hill Notation):
C35H58N5O11P
CAS Number:
Molecular Weight:
755.84
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
18:1-06:0 NBD PE, Avanti Research™ - A Croda Brand 810155C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810155C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810155C
concentration
1 mg/mL (810155C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.
Application
18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.
Biochem/physiol Actions
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.
Packaging
5 mL Amber Glass Screw Cap Vial (810155C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
易制毒化学品（2类）
危险化学品
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Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
Kalienkova V, et al.
eLife, 37-50 (2012)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
FEBS Journal, 37-50 (2012)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
Fluorescent methods to study biological membranes, 37-50 (2012)
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids, 37-50 (2012)
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