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Merck
CN

810161C

Avanti

14:0-06:0 NBD PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-myristoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-[phospho-rac-(1-glycerol)] (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C32H56N5O13P
CAS Number:
474942-84-2
Molecular Weight:
749.79
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

14:0-06:0 NBD PG, Avanti Research™ - A Croda Brand 810161C

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810161C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810161C

concentration

1 mg/mL (810161C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

NBD PG is a phosphatidylglycerol (PG) lipid labeled with the 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) fluorophore. Phosphatidylglycerol (PG) is localized to alveoli and is mostly found in the pulmonary surfactant.

Biochem/physiol Actions

7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) labeled fluorescence probes play an important role in the study of model membranes. NBD labeled phosphatidylglycerol (PG) serves as a fluorescent substrate in the enzyme assays. PG contributes to the protection against viral infection and is known to be involved in the inflammatory mechanism.

Packaging

5 mL Amber Glass Screw Cap Vial (810161C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

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Chi-Jung Weng et al.
Molecular membrane biology, 33(1-2), 23-28 (2016-07-28)
To investigate the effect of fluorescent probe on the properties of membranes, we studied model membranes composed of 1,2- dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1-palmitoyl 2-oleoyl-sn-glycero-3-phosphocholine (POPC) in the presence and absence of fluorescent probe. The morphology of giant unilamellar vesicles (GUVs)
Rachel Fickes et al.
Rapid communications in mass spectrometry : RCM, 30(24), 2601-2606 (2016-10-01)
Structural analogs of the bioactive lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol were synthesized with a xylitol polar head group and both diacyl and diether radyl groups. Mass spectral characterization of xylitol phospholipids (PX) was carried out using collisional activation and high-resolution mass measurements of
Maria Karatsa-Dodgson et al.
Journal of bacteriology, 192(20), 5341-5349 (2010-08-17)
Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria. The key enzyme responsible for polyglycerolphosphate lipoteichoic acid synthesis in the Gram-positive pathogen Staphylococcus aureus is the membrane-embedded lipoteichoic acid synthase enzyme, LtaS. It is presumed that LtaS

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