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About This Item
Empirical Formula (Hill Notation):
C36H61N6O13P
CAS Number:
Molecular Weight:
816.88
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
18:1-06:0 NBD PS, Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810194P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
Application
18:1-06:0 NBD PS or 1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used as a marker to determine the aminophospholipid transferase activity and in large unilammelar vesicles (LUVs) to investigate the role of phosphatidylinositol 4,5-bisphosphate (PIP2).
Biochem/physiol Actions
Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It supports neuronal survival, neurite growth and synaptogenesis. It is associated with cognitive disability in Alzheimer′s disease.
General description
Phosphatidylserine (PS) is an acidic phospholipid enriched in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues. NBD PS is a fluorescently labeled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
Packaging
5 mL Amber Glass Screw Cap Vial (810194P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
Metabolism and functions of phosphatidylserine
Vance JE and Steenbergen R
Progress in Lipid Research null
R A Zager et al.
Kidney international, 55(1), 148-159 (1999-01-20)
Fluorinated anesthetics can profoundly alter plasma membrane structure and function, potentially impacting cell injury responses. Because major surgery often precipitates acute renal failure, this study assessed whether the most commonly used fluorinated anesthetic, isoflurane, alters tubular cell responses to toxic
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research null
Involvement of phosphatidylinositol 4, 5-bisphosphate in phosphatidylserine exposure in platelets: use of a permeant phosphoinositide-binding peptide
Bucki R, et al.
Biochemistry null
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