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Merck
CN

810223C

Avanti

C12-NBD Glucosyl Ceramide

Avanti Research™ - A Croda Brand

Synonym(s):

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-glucosyl-β1-1′-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C42H71N5O11
CAS Number:
474943-01-6
Molecular Weight:
822.04
MDL number:
MFCD22570234
NACRES:
NA.25
UNSPSC Code:
12352211

Key Documents

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Product Name

C12-NBD Glucosyl Ceramide, Avanti Research™ - A Croda Brand 810223C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810223C-250ug)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810223C

concentration

0.25 mg/mL (810223C-250ug)

shipped in

dry ice

storage temp.

−20°C

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Application

C12-NBD Glucosyl Ceramide is suitable for liposome preparation.

Biochem/physiol Actions

Glucosyl ceramide (GlcCer) is produced by GlcCer synthase from ceramide in the cytosolic membranes of Golgi. In the luminal Golgi membrane, GlcCer participates in the generation of glycosphingolipids.

Packaging

5 mL Amber Glass Screw Cap Vial (810223C-250ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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The effects of chemically synthesized saposin C on glucosylceramide-beta-glucosidase
Yoneshige A, et al.
Clinical Biochemistry, 48(16-17), 1177-1180 (2015)
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide
D?Angelo G, et al.
Nature, 449(7158), 62-62 (2007)

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