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Merck
CN

810346C

Avanti

18:0 Cyanine 5.5 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(Cyanine 5.5)

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About This Item

Empirical Formula (Hill Notation):
C81H126ClN4O9P
CAS Number:
2260669-71-2
Molecular Weight:
1366.32
MDL number:
MFCD00133427
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

18:0 Cyanine 5.5 PE, Avanti Research™ - A Croda Brand

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810346C-1mg)
pkg of 5 × 1 mL (810346C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (810346C-1mg)
1 mg/mL (810346C-5mg)

lipid type

fluorescent lipids

shipped in

dry ice

storage temp.

−20°C

General description

18:0 Cy5.5 PE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(Cyanine 5.5) is a phosphoethanolamine (PE) derivative wherein the amine and hydroxyl groups of PE are substituted with cyanine 5.5 and distearoyl-sn-glycerol.

Application

18:0 Cy5.5 PE has been used in the preparation of fluorescently labelled liposomes, for direct visualization of nitrobenzoxadiazole (NBD)-palmitoyl-CoA association with a liposome. It has also been used to fluorescently label small unilamellar vesicles (SUV) and large unilamellar vesicles (LUV) to study the interaction of viral particles with phospholipids.

Packaging

5 mL Amber Glass Screw Cap Vial (810346C-1mg)
5 mL Amber Glass Screw Cap Vial (810346C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品
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Oleksandr Kolyvushko et al.
Pathogens (Basel, Switzerland), 9(5) (2020-05-14)
Exposure of phosphatidylserine (PS) in the outer leaflet of the plasma membrane is induced by infection with several members of the Alphaherpesvirinae subfamily. There is evidence that PS is used by the equine herpesvirus type 1 (EHV-1) during entry, but
James J Asciolla et al.
Cell reports, 29(13), 4608-4619 (2019-12-26)
Attachment of palmitate to the N terminus of Sonic hedgehog (Shh) is essential for Shh signaling. Shh palmitoylation is catalyzed on the luminal side of the endoplasmic reticulum (ER) by Hedgehog acyltransferase (Hhat), an ER-resident enzyme. Palmitoyl-coenzyme A (CoA), the

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