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About This Item
Empirical Formula (Hill Notation):
C25H49N2O2
CAS Number:
Molecular Weight:
409.67
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
powder
Product Name
4-palmitamido-TEMPO, N-tempoyl palmitamide, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810610P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810610P
lipid type
ESR probes
shipped in
dry ice
storage temp.
−20°C
General description
4-palmitamido-TEMPO/N-tempoyl-palmitamide is a spin label, that is present in the polar head-group region of the membrane.
This amphiphilic compound binds strongly to membranes by virture of its long hydrocarbon chain, but the polarity of the amide linkage is expected to localize the nitroxide function in the aqueous phase adjacent to the membrane surface. The location of the nitroxide function allows one to investigate electrostatic potentials and lipid-protein interactions at the membrane surface.
Application
4-palmitamido-TEMPO/N-tempoyl palmitamide (N-TP) may be used:
- to enrich rod outer segment (ROS) membranes
- as a spin probe in vesicles/bilayer to prepare samples for electron spin resonance (ESR) experiments
- as a component in liposomes to assess the mobility of lipid headgroups
Packaging
5 mL Amber Glass Screw Cap Vial (810610P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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Ciara C M Lally et al.
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Shani Ben-Zichri et al.
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Curcumin, the main molecular ingredient of the turmeric spice, has been reported to exhibit therapeutic properties for varied diseases and pathological conditions. While curcumin appears to trigger multiple signaling pathways, the precise mechanisms accounting for its therapeutic activity have not
Y K Shin et al.
Biophysical journal, 61(6), 1443-1453 (1992-06-01)
A new general method for the determination of electrostatic potentials at biological surfaces is presented. The approach is based on measurement of the collision frequency of a charged nitroxide in solution with a nitroxide fixed to the surface at the
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