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About This Item
CAS Number:
UNSPSC Code:
12352211
Product Name
E. coli CA, Avanti Research™ - A Croda Brand 841199P, powder
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (841199P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 841199P
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=P([O-])(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCCC)=O)COC(CCCCCCCCCCCCCC)=O)OCC([H])(O)COP([O-])(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C/CCCCCCCC)=O)=O.[Na+].[Na+]
General description
Cardiolipin is the most important phospholipid of mitochondria. E.coli membrane consists 5-10% of cardiolipin. Cardiolipin is a non-bilayer anionic phospholipid, which has four acyl chains and small headgroup.
Application
E. coli CA has been used for western blotting. It has also been used for lipid monolayer assay.
Biochem/physiol Actions
Cardiolipin plays a major role in the dynamic organization of membranes and in cell division. It is implicated in proton uptake pathway.
Packaging
5 mL Clear Glass Sealed Ampule (841199P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
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Exclusion of assembled M re B by anionic phospholipids at cell poles confers cell polarity for bidirectional growth
Kawazura T, et al.
Molecular Microbiology, 104(3), 472-486 (2017)
Hydrobiologia, 104(3), 472-486 (2018)
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
Targeting bacterial cardiolipin enriched microdomains: an antimicrobial strategy used by amphiphilic aminoglycoside antibiotics
El Khoury M, et al.
Scientific reports, 7(1), 10697-10697 (2017)
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