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Merck
CN

850303C

Avanti

04:0 PC

Avanti Research™ - A Croda Brand

Synonym(s):

PC(4:0/4:0)

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About This Item

Empirical Formula (Hill Notation):
C16H32NO8P
CAS Number:
3355-26-8
Molecular Weight:
397.40
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

04:0 PC, 1,2-dibutyryl-sn-glycero-3-phosphocholine, chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850303C-25mg)
pkg of 1 × 20 mL (850303C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850303C

concentration

10 mg/mL (850303C-25mg)
25 mg/mL (850303C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1

InChI key

QIJYAMAPPUXBSC-CQSZACIVSA-N

General description

Phosphatidylcholine (PC) is dietary source of choline. 04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) is a short chain fatty acyl residue.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

04:0 PC (1,2-dibutyryl-sn-glycero-3-phosphocholine) may be used:
  • to study its influence on the formation of lipid hydroperoxides and headspace hexanal in stripped soybean oil (SSO)
  • to study its impact on the antioxidant activity of α-tocopherol
  • as a phospholipid substrate to study the substrate specificity of the purified glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP)
  • as a substrate to study the activities of soluble and immobilized phospholipase 2 from snake venom

Biochem/physiol Actions

Phosphatidylcholine (PC) intake through diet can enhance the learning and memory ability in rats.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850303C-500mg)
5 mL Clear Glass Sealed Ampule (850303C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

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Bingcan Chen et al.
Food & function, 2(6), 302-309 (2011-07-23)
Phospholipids self-assemble in bulk oils to form structures such as reverse micelles that can alter the microenvironment where chemical degradation reactions occur, such as lipid oxidation. In this study, we examined the influence of phospholipid reverse micelles on the activity
Z Shen et al.
Journal of lipid research, 36(5), 1147-1151 (1995-05-01)
A new method for the immobilization of phospholipase A2 (PLA2) has been developed to enhance the activity retention of immobilized PLA2. When PLA2 from the venom of Agkistrodon piscivorus piscivorus was pretreated with 4-nitro-3-octanoyl-oxybenzoic acid to acylate epsilon-amino groups of
F Berr et al.
The Journal of biological chemistry, 268(6), 3976-3979 (1993-02-25)
In the present study we used the water-soluble short chain phosphatidylcholine analogue L-alpha-dibutyryl-glycero-3-phosphatidylcholine (diC4PC) to investigate the mechanism involved in the canalicular secretion of phospholipids in rat liver. Uptake of 14C-labeled di-C4PC was studied in isolated microsomes as well as
Shingo Mineta et al.
Journal of bioscience and bioengineering, 119(2), 123-130 (2014-08-20)
Streptomyces sanglieri extracellularly produces a glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP). The gene encoding the enzyme was found to consist of a 2124-bp ORF, which codes for an N-terminal 48 residue signal peptide required for secretion and a 660 amino acid mature protein
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
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