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About This Item
Empirical Formula (Hill Notation):
C45H86NO8P
CAS Number:
Molecular Weight:
800.14
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
DOCPe, Avanti Research™ - A Croda Brand 850312C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850312C-25mg), pkg of 2 × 4 mL (850312C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850312C
concentration
10 mg/mL (850312C-25mg), 25 mg/mL (850312C-200mg)
shipped in
dry ice
storage temp.
−20°C
General description
2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethylphosphate (DOCPe) is a neutrally charged lipid.
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.
Application
DOCPe is suitable for liposomes preparation. It is also suitable to use as membrane to examine the impact of the phospholipid head on peptide-membrane interaction.
Packaging
5 mL Clear Glass Sealed Ampule (850312C-200mg)
5 mL Clear Glass Sealed Ampule (850312C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
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Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles
Wang X, et al.
Langmuir (2018)
Partition of Positively and Negatively Charged Tryptophan Ions in Membranes with Inverted Phospholipid Heads: Simulations and Experiments
Cardenas AE, et al.
The Journal of Physical Chemistry B, 123(15), 3272-3281 (2019)
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850312C-200MG | 04061837791925 |