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Merck
CN

850350C

Avanti

15:0 PC

Avanti Research™ - A Croda Brand

Synonym(s):

PC(15:0/15:0)

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About This Item

Empirical Formula (Hill Notation):
C38H76NO8P
CAS Number:
3355-27-9
Molecular Weight:
705.99
MDL number:
MFCD00063522
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

15:0 PC, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)(OCC[N+](C)(C)C)(OCC(OC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)O

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39(3,4)5)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/p+1

InChI key

LJARBVLDSOWRJT-UHFFFAOYSA-O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850350C-25mg), pkg of 2 × 4 mL (850350C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850350C

concentration

10 mg/mL (850350C-25mg), 25 mg/mL (850350C-200mg)

shipped in

dry ice

storage temp.

−20°C

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General description

Phosphatidylcholine (PC) carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

15:0 PC (1,2-dipentadecanoyl-sn-glycero-3-phosphocholine) may be used:
  • as a component in fluidizing lipid bilayers to study the role of membrane fluidity in mediating membrane sensitivity to small hydrophobic peptides or haptoglobin-related protein (SHP-1)
  • to prepare giant unilamellar lipid vesicles (GUVs)
  • to construct supported phospholipid bilayers to study the gel-fluid phase transition behavior using in situ, temperature-dependent atomic force microscopy

Biochem/physiol Actions

Phosphatidylcholine (PC) is capable of preventing the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.

Packaging

5 mL Clear Glass Sealed Ampule (850350C-200mg)
5 mL Clear Glass Sealed Ampule (850350C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品
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Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Z Vivian Feng et al.
Biophysical journal, 88(3), 2154-2164 (2004-12-15)
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Thomas Andersen et al.
Soft matter, 10(24), 4268-4274 (2014-05-02)
We reveal that the gel to fluid phase transition causes spherical membrane vesicles to release a finite number of molecules in several consecutive and localized events. By locally melting Giant Unilamellar lipid Vesicles (GUVs), using an optically trapped gold nanoparticle
M U Rasheed et al.
The Science of the total environment, 733, 139110-139110 (2020-05-25)
Increased soil nitrogen (N), warming and bark herbivory all are expected to affect boreal forests in the future. We studied the effects of warming (0.5 °C and 4.0 °C above ambient air and soil temperature, respectively), moderate N addition (30 kg N ha-1 y-1) and bark
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