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850360P

Avanti

17:0 PC

1,2-diheptadecanoyl-sn-glycero-3-phosphocholine, powder

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Synonym(s):
PC(17:0/17:0)
Empirical Formula (Hill Notation):
C42H84NO8P
CAS Number:
70897-27-7
Molecular Weight:
762.09
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850360P-200mg)
pkg of 1 × 25 mg (850360P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850360P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3

InChI key

RTWAYAIMWLNAJW-UHFFFAOYSA-N

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are attached to a glycerol molecule covalently with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

17:0 PC (1,2-diheptadecanoyl-sn-glycero-3-phosphocholine) has been used:
  • as an internal standard for phospholipids in fatty acid analysis
  • as a component in the extraction mixture for lipid extraction from frozen leaf tissue
  • as an internal standard and a component in methanol: methyl tert-butyl ether (MTBE) extraction buffer for the determination of metabolite levels in tumor and normal tissues using gas chromatography-mass spectrometrometer (GC-MS)

Biochem/physiol Actions

Phosphatidylcholines (PCs) serve as a major source for eicosanoids.

Packaging

5 mL Amber Glass Screw Cap Vial (850360P-200mg)
5 mL Amber Glass Screw Cap Vial (850360P-25mg)

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

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Kristin A Marks et al.
Prostaglandins, leukotrienes, and essential fatty acids, 89(2-3), 89-96 (2013-06-20)
Sex differences in monounsaturated fatty acid (MUFA) levels suggest ovarian hormones may affect MUFA biosynthesis. Sprague-Dawley rats (8 weeks of age) were ovariectomized or sham operated with ovariectomized rats implanted with a constant-release hormone pellet providing 17β-estradiol, progesterone, both or
Dawid Perlikowski et al.
Frontiers in plant science, 7, 1027-1027 (2016-08-04)
Drought tolerant plant genotypes are able to maintain stability and integrity of cellular membranes in unfavorable conditions, and to regenerate damaged membranes after stress cessation. The profiling of cellular glycerolipids during drought stress performed on model species such as Arabidopsis
Joanna Bogusławska et al.
Cancers, 11(12) (2019-11-24)
Metabolic reprogramming is one of the hallmarks of renal cell cancer (RCC). We hypothesized that altered metabolism of RCC cells results from dysregulation of microRNAs targeting metabolically relevant genes. Combined large-scale transcriptomic and metabolic analysis of RCC patients tissue samples
Taly Lapidot-Cohen et al.
Current protocols in plant biology, 5(2), e20109-e20109 (2020-04-29)
Lipids are fascinating due to their chemical diversity, which is especially vast in the plant kingdom thanks to the high plasticity of the plant biosynthetic machinery. Lipidomic studies aim to simultaneously analyze a large number of lipid compounds of diverse
Leonardo Perez de Souza et al.
Current protocols in plant biology, 4(4), e20100-e20100 (2019-11-20)
Metabolomics has grown into one of the major approaches for systems biology studies, in part driven by developments in mass spectrometry (MS), providing high sensitivity and coverage of the metabolome at high throughput. Untargeted metabolomics allows for the investigation of
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