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Merck
CN

850366C

Avanti

18:0 (9,10dibromo) PC

Avanti Research - A Croda Brand

Synonym(s):

1,2-di-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C44H84NO8PBr4
CAS Number:
Molecular Weight:
1105.73
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
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Product Name

18:0 (9,10dibromo) PC, 1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (850366C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850366C

concentration

10 mg/mL (850366C-10mg)

shipped in

dry ice

storage temp.

−20°C

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General description

18:0 (9,10dibromo) PC (1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine) is a zwitterionic brominated phospholipid.

Application

18:0 (9,10dibromo) PC (1,2-di-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine) may be used:
  • in the preparation of liposomes/small unilamellar vesicles (SUVs)
  • in the preparation of large unilamellar vesicles (LUVs) to facilitate vesicles sedimentation
  • as a component in liposomes

Biochem/physiol Actions

Phosphatidylcholine (PC) forms a hydrophobic surface in the mucus by acting as a surfactant resulting in the inhibition of penetrance of bacteria.

Packaging

5 mL Clear Glass Sealed Ampule (850366C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Maria Jesús Sánchez-Martín et al.
Journal of colloid and interface science, 360(1), 124-131 (2011-05-14)
The aim of this study was to identify proteins that could inhibit the activity of the peptide sequence representing the N-terminal of the surface protein gp41 of HIV, corresponding to the fusion peptide of the virus (HIV-1 FP). To do
Olatz Landeta et al.
The Journal of biological chemistry, 286(10), 8213-8230 (2011-01-05)
BAK is a key effector of mitochondrial outer membrane permeabilization (MOMP) whose molecular mechanism of action remains to be fully dissected in intact cells, mainly due to the inherent complexity of the intracellular apoptotic machinery. Here we show that the
Jocelyn Méré et al.
The Biochemical journal, 386(Pt 1), 47-56 (2004-11-06)
Gelsolin is a calcium-, pH- and lipid-dependent actin filament severing/capping protein whose main function is to regulate the assembly state of the actin cytoskeleton. Gelsolin is associated with membranes in cells, and it is generally assumed that this interaction is

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