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Merck
CN

850372C

Avanti

23:0 PC

Avanti Research™ - A Croda Brand

Synonym(s):

PC(23:0/23:0)

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About This Item

Empirical Formula (Hill Notation):
C54H108NO8P
CAS Number:
112241-60-8
Molecular Weight:
930.41
MDL number:
MFCD00674311
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

23:0 PC, 1,2-ditricosanoyl-sn-glycero-3-phosphocholine, chloroform

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C54H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-53(56)60-50-52(51-62-64(58,59)61-49-48-55(3,4)5)63-54(57)47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h52H,6-51H2,1-5H3/t52-/m1/s1

InChI key

XGMMADXONKETMF-OIVUAWODSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850372C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850372C

concentration

10 mg/mL (850372C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

23:0 PC may be used:
  • in unilamellar liposomes preparation to study its interaction with single-strand phosphorothioate oligonucleotides (ONs)
  • as an internal standard to validate the extracted lipids from bovine plasma
  • as an internal standard to quantify fatty acids and cholesterol in H1299 cells

Biochem/physiol Actions

High or low level of phosphatidylcholine (PC) can affect energy metabolism in several organelles.

General description

Phosphatidylcholine (PC), an endogenous lipid, found in the secretion of bile is ubiquitously present in the tissues of animals.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Packaging

5 mL Clear Glass Sealed Ampule (850372C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

Regulatory Information

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Improving bioavailability of nutraceuticals by nanoemulsification
Nutraceuticals, 4, 481-534 (2016)
Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
Dongmei Lu et al.
Biochimica et biophysica acta, 1563(1-2), 45-52 (2002-05-15)
Although double-stranded DNA (dsDNA) has been shown to bind to zwitterionic lipids, it has been reported that this association is stronger for disordered (L(alpha)) phase lipids than for well-ordered (L(beta)) lipids. In this work, the interaction of single-strand phosphorothioate oligonucleotides
Joseph P Argus et al.
Journal of lipid research, 58(2), 460-468 (2016-12-16)
Stable isotope labeling has become an important methodology for determining lipid metabolic parameters of normal and neoplastic cells. Conventional methods for fatty acid and cholesterol analysis have one or more issues that limit their utility for in vitro stable isotope-labeling
S Imhasly et al.
BMC veterinary research, 11, 252-252 (2015-10-09)
The transition period of dairy cows, around parturition and the onset of lactation, involves endocrine and metabolic changes to compensate for an increased energy requirement aggravated by reduced feed intake. Transition cows adjust to the resulting negative energy balance with
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