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850408P

Avanti

4ME 16:0 PS

1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

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Synonym(s):
1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))
Empirical Formula (Hill Notation):
C46H89NO10PNa
CAS Number:
474967-76-5
Molecular Weight:
870.16
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (850408P-10mg)
pkg of 1 × 25 mg (850408P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850408P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O.[Na+]

General description

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine) is a sodium salt of a fatty acid modified lipid.

Application

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt)) may be used as a component in planar lipid bilayer and in asymmetrical leaflets to study the translocation of β-galactosidase (β-gal) across an asymmetric bilayer. It may be used as an internal standard in electrospray ionization-mass spectrometry (ESI-MS/MS) analysis.

Biochem/physiol Actions

Diphytanoyl lipids are mainly used in electrophysiological experiments.

Packaging

5 mL Clear Glass Sealed Ampule (850408P-10mg)
5 mL Clear Glass Sealed Ampule (850408P-25mg)

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

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Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6(10), 1849e-1849e null
Elsa Bárány-Wallje et al.
Biophysical journal, 89(4), 2513-2521 (2005-07-26)
Penetratin is a short, basic cell-penetrating peptide able to induce cellular uptake of a vast variety of large, hydrophilic cargos. We have reassessed the highly controversial issue of direct permeation of the strongly cationic peptide across negatively charged lipid membranes.
Xin Li et al.
Analytical chemistry, 89(22), 12369-12374 (2017-10-21)
Pep-1 is a cell-penetrating peptide that represents a powerful strategy for delivering large, hydrophilic therapeutic molecules into cells. Model membranes, such as lipid vesicles and planar bilayers, have been useful for investigating the direct translocation of cell-penetrating peptides. Here, we
Daniel L Burden et al.
Langmuir : the ACS journal of surfaces and colloids, 34(37), 10847-10855 (2018-08-29)
All cells in all domains of life possess a cytoskeleton that provides mechanical resistance to deformation and general stability to the plasma membrane. Here, we utilize a two-dimensional scaffolding created by actin filaments to convey mechanical support upon relatively fragile
Alessio Sacconi et al.
Langmuir : the ACS journal of surfaces and colloids, 34(40), 12183-12190 (2018-09-16)
Solid supported membranes (SSMs) are usually formed by an hybrid octadecanethiol/phosphatidylcholine (PC) bilayer supported by a gold electrode. Recently, it was shown that phosphatidylserine (PS) in place of PC can promote a more effective accumulation of lipid vesicles on the
View All Related Papers

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