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About This Item
Empirical Formula (Hill Notation):
C40H80NO8P
CAS Number:
Molecular Weight:
734.04
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
18:0-14:0 PC, 1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine, chloroform
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850464C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850464C
concentration
10 mg/mL (850464C-25mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) is a major bilayer-forming phospholipid in which the headgroup carries a positively and negatively charged quaternary amine and a phosphate, respectively.
Application
18:0-14:0 PC (1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine) may be used in liposomes to study its interference in the proliferation of several cell lines using transmission electron microscopy (TEM).
Biochem/physiol Actions
Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.
Packaging
5 mL Clear Glass Sealed Ampule (850464C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
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Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Anna Werlein et al.
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features
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