Skip to Content
Merck
CN

850465C

Avanti

18:0-16:0 PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; SPPC; PC(18:0/16:0)

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C42H84NO8P
CAS Number:
59403-53-1
Molecular Weight:
762.09
UNSPSC Code:
12352211

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

18:0-16:0 PC, 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850465C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850465C

concentration

10 mg/mL (850465C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholines (PCs) are amphipathic molecules, which accounts for approximately 40−50% of the total cellular phospholipids. 18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is an asymmetric lipid.

Application

18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • in bilayer membranes to study the thermodynamic properties of phase transitions
  • as a carrier in unilamellar vesicles to evaluate the fragmentation of hydroperoxy endoperoxide 13-HP-Endo-PC in a model membrane
  • as a lipid standard in liquid chromatography−mass spectrometry analysis

Biochem/physiol Actions

Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.

Packaging

5 mL Clear Glass Sealed Ampule (850465C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 (2018)
Xiaodong Gu et al.
Chemical research in toxicology, 24(7), 1080-1093 (2011-05-17)
Biologically active phospholipids that incorporate an oxidatively truncated acyl chain terminated by a γ-hydroxyalkenal are generated in vivo. The γ-hydroxyalkenal moiety protrudes from lipid bilayers like whiskers that serve as ligands for the scavenger receptor CD36, fostering endocytosis, e.g., of
Masaki Goto et al.
Biochimica et biophysica acta, 1778(4), 1067-1078 (2008-01-15)
The bilayer phase transitions of palmitoylstearoyl-phosphatidylcholine (PSPC), diheptadecanoyl-PC (C17PC) and stearoylpalmitoyl-PC (SPPC) which have the same total carbon numbers in the two acyl chains were observed by differential scanning calorimetry and high-pressure optical method. As the temperature increased, these bilayers
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service