Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C17H32O4
CAS Number:
Molecular Weight:
300.43
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
7.7 MAG, Avanti Research™ - A Croda Brand 850530O
assay
>99% (TLC)
form
oil
mol wt
300.43 g/mol
packaging
pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850530O
technique(s)
protein sequencing: suitable
shipped in
dry ice
storage temp.
−20°C
Application
7.7 MAG may be used as a host lipid in MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex for crystallization by lipidic cubic phase (LCP) method.
Biochem/physiol Actions
Monoacylglycerols (MAGs) are used in food industry as emulsifiers. 7.7 MAG participates in meso crystallization of BtuB (vitamin B12 transporter), an outer membrane protein. It can also help in lysozyme crystal growth. 7.7 MAG also plays a key role in the growth of diffraction-quality crystals. MAGs holds high significance in pharmaceutical and food industry.
General description
Monoacylglycerols (MAGs) are glycerol esters. 7.7 MAG has a 14 carbon acyl chain and possess a bilayer thickness of 25.8 Å.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.
Packaging
5 mL PTFE Vial with Screw Cap (850530O-200mg)
5 mL PTFE Vial with Screw Cap (850530O-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Synthesis and characterization of monoacylglycerols through glycerolysis of ethyl esters derived from linseed oil by green processes
Hobuss CB, et al.
Royal Society of Chemistry Advances, 10, 2327-2336 (2020)
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance
Related Content
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service