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About This Item
Empirical Formula (Hill Notation):
C25H50NO8P
CAS Number:
Molecular Weight:
523.64
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
10:0 PE, 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine, powder
InChI key
KKOSJVWUOHEQKA-HSZRJFAPSA-N
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850700P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850700P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.
Application
10:0 PE has been used for the synthesis of fluorescent phospholipid derivative NBD-didecanoylphosphatidylethanolamine (NBD-diC10PE).
Biochem/physiol Actions
Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.
Packaging
5 mL Clear Glass Sealed Ampule (850700P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Binding of phospholipids to beta-Lactoglobulin and their transfer to lipid bilayers
Martins PAT, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(5), 1308-1315 (2008)
The Membranes of Cells (2016)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831, 543-554 (2013)
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)
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