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850705P

Avanti

16:0 PE

Avanti Polar Lipids

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Synonym(s):
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine; DPPE; PE(16:0/16:0); 110633
Empirical Formula (Hill Notation):
C37H74NO8P
CAS Number:
Molecular Weight:
691.96
NACRES:
NA.25

description

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850705P-1g)
pkg of 1 × 200 mg (850705P-200mg)
pkg of 1 × 25 mg (850705P-25mg)
pkg of 1 × 500 mg (850705P-500mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C37H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(39)43-33-35(34-45-47(41,42)44-32-31-38)46-37(40)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35H,3-34,38H2,1-2H3,(H,41,42)/t35-/m1/s1

InChI key

SLKDGVPOSSLUAI-PGUFJCEWSA-N

General description

Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in biological membranes. It is found in nervous tissue.

Application

16:0 PE has been used:
  • for the preparation of perfluorocarbon (PFC) nanoparticles
  • for lipid binding by liposome flotation assays
  • to characterize the metabolic fate of synaptamide in a dopaminergic cell line

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It plays a vital role in autophagy, cell division and protein folding. Phosphatidylethanolamine functions as a precursor for the synthesis of various protein modifications. It controls membrane fluidity in eukaryotic cells. Phosphatidylethanolamine behaves as an intermediate for the synthesis of glycerophospholipid classes.

Packaging

20 mL Clear Glass Screw Cap Vial (850705P-1g)
20 mL Clear Glass Screw Cap Vial (850705P-500mg)
5 mL Amber Glass Screw Cap Vial (850705P-200mg)
5 mL Amber Glass Screw Cap Vial (850705P-25mg)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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705578-5MG-PW

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1000309185

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An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Metabolic studies of synaptamide in an immortalized dopaminergic cell line
Sonti S, et al.
Prostaglandins & other lipid mediators, 141, 25-33 (2019)
The Membranes of Cells (2016)
Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice
Pan H, et al.
International journal of nanomedicine, 13, 5187-5187 (2018)
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease
Hernandez-Alvarez MI, et al.
Cell, 177(4), 881-895 (2019)

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