850815P
Avanti
18:1 Hemi BMP-d5 (R, R/S)
>99%, Avanti Research™ - A Croda Brand
Synonym(s):
Rac-(3-oleoyl-2-hydroxy)-glycerol(d5)-1-phospho-sn-3′-(1′,2′-dioleoyl)-glycerol (ammonium salt)
biological source
synthetic
description
Stable Isotope
Assay
>99%
form
powder
functional group
phospholipid
storage temp.
−20°C
General description
Bis(monoacylglycerol)phosphates (BMP) are a class of lipids that play an important role in lysosomal integrity and function. BMPs are negatively charged glycerophospholipids and are not found in high concentrations in most mammalian cells, but in cells such as macrophages, the concentration of BMP is much higher. BMP is often dysregulated in lysosomal storage disorders. Recent studies have shown that BMP can be an important biomarker for detecting metastatic cancer, certain lysosomal storage disorders, or drug-induced phospholipidosis. Largely uncharacterized, BMP metabolism remains an understudied lipid metabolic pathway that could lead to a better understanding of lysosomal storage disorders.
Application
Lipids Research
Features and Benefits
This BMP is the deuterated version, which will enable the easier study of structure, dynamics, and function of cell membranes.
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Regulatory Information
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