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Merck
CN

850815P

Avanti

18:1 Hemi BMP-d5 (R, R/S)

Avanti Research - A Croda Brand

Synonym(s):

Rac-(3-oleoyl-2-hydroxy)-glycerol(d5)-1-phospho-sn-3′-(1′,2′-dioleoyl)-glycerol (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C60H109D5NO11P
CAS Number:
Molecular Weight:
1061.55
UNSPSC Code:
12352211
NACRES:
NA.21
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SMILES string

[NH4+].[2H]C([2H])(OC(=O)CCCCCCC\C=C/CCCCCCCC)C([2H])(O)C([2H])([2H])OP([O-])(=O)OC[C@@H](COC(=O)CCCCCCC\C=C/CCCCCCCC)OC(=O)CCCCCCC\C=C/CCCCCCCC

biological source

synthetic

description

Stable Isotope

assay

>99%

form

powder

packaging

pkg of 1 × 25 mg 850815P-25MG

manufacturer/tradename

Avanti Research - A Croda Brand

solubility

water: soluble at 20 °C

functional group

phospholipid

shipped in

dry ice

storage temp.

−20°C

General description

Bis(monoacylglycerol)phosphates (BMP) are a class of lipids that play an important role in lysosomal integrity and function. BMPs are negatively charged glycerophospholipids and are not found in high concentrations in most mammalian cells, but in cells such as macrophages, the concentration of BMP is much higher. BMP is often dysregulated in lysosomal storage disorders. Recent studies have shown that BMP can be an important biomarker for detecting metastatic cancer, certain lysosomal storage disorders, or drug-induced phospholipidosis. Largely uncharacterized, BMP metabolism remains an understudied lipid metabolic pathway that could lead to a better understanding of lysosomal storage disorders.

Application

Lipids Research

Features and Benefits

This BMP is the deuterated version, which will enable the easier study of structure, dynamics, and function of cell membranes.

Packaging

5 mL Amber Glass Screw Cap Vial (850815P-25MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

Regulatory Information

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