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855175C

Avanti

06:0 Lyso PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-hexanoyl-sn-glycero-3-phosphocholine; PC(6:0/0:0)

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About This Item

Empirical Formula (Hill Notation):
C14H30NO7P
CAS Number:
58445-96-8
Molecular Weight:
355.36
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

06:0 Lyso PC, 1-hexanoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (855175C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 855175C

concentration

10 mg/mL (855175C-25mg)

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C14H30NO7P/c1-5-6-7-8-14(17)20-11-13(16)12-22-23(18,19)21-10-9-15(2,3)4/h13,16H,5-12H2,1-4H3/t13-/m1/s1

InChI key

WDNDPXJAUNUOFK-CYBMUJFWSA-N

General description

06:0 Lyso PC is a natural lysophosphatidylcholine. Lysophosphatidylcholine (Lyso-PC) is a constituent of blood plasma, vascular tissue and lipoproteins. It is a bioactive proinflammatory lipid, produced on pathological response.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso-PC) is linked to inflammatory diseases and atherosclerosis. It enhances the expression of genes for growth factors and cellular adhesion molecules.

Packaging

5 mL Clear Glass Sealed Ampule (855175C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous quantification of mammal lysophosphatidylcholines and lysophosphatidylethanolamines in serum
Suarez-Garcia S, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1055, 86-97 (2017)
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)
View All Related Papers

Global Trade Item Number

SKUGTIN
855175C-25MG04061837792908