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855725C

Avanti

2-18:1 Lyso PE

Avanti Polar Lipids, chloroform solution

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Synonym(s):
1-Hydroxy-2-oleoyl-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C23H46NO7P
CAS Number:
60701-97-5
Molecular Weight:
479.59
NACRES:
NA.25

Assay

>99% (TLC)

form

chloroform solution

packaging

pkg of 1 × 1 mL (855725C-10MG)
pkg of 1 × 1 mL (855725C-1MG)
pkg of 1 × 1 mL (855725C-5MG)

manufacturer/tradename

Avanti Polar Lipids

concentration

1 mg/mL in chloroform (855725C-1MG)
10 mg/mL in chloroform (855725C-10MG)
5 mg/mL in chloroform (855725C-5MG)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO)=O

General description

2-18:1 Lyso PE is a lyso phosphatidylethanolamine with oleic acid substitution at sn-2 position. LPE is synthesized from phosphatidylethanolamine (PE) through the action of phospholipase A.

Application

2-18:1 Lyso PE is suitable for use as standard, as sn-2 isomers of lyso PE for hydrophilic interaction liquid chromatography-paired with ion mobility-mass spectrometry (HILIC-IM-MS), and high performance thin-layer chromatography (HPTLC).

Biochem/physiol Actions

Lyso phosphatidylethanolamine (Lyso PE) is a lipid present naturally in plants and it retards senescence in leaves, postharvest fruits and flowers. LPE has antifungal and antibacterial activity. LPE functions to induce neuronal differentiation, increases intracellular calcium, stimulates chemotactic migration and cellular invasion in cancer cells.

Packaging

5 mL Clear Glass Sealed Ampule (855725C-1MG, 855725C-5MG, and 855725C-10MG)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

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Trypanosoma cruzi epimastigotes store cholesteryl esters in lipid droplets after cholesterol endocytosis.
Pereira MG, et al.
Molecular and Biochemical Parasitology, 224, 6-16 (2018)
Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol.
Makide K, et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009)
Inhibition of phospholipase D by lysophosphatidylethanolamine, a lipid-derived senescence retardant.
Ryu SB, et al.
Proceedings of the National Academy of Sciences of the USA, 94(23), 12717-12721 (1997)
Lipidomic consequences of phospholipid synthesis defects in Escherichia coli revealed by HILIC-ion mobility-mass spectrometry.
Hines KM and Xu L
Chemistry and Physics of Lipids, 219, 15-22 (2019)

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