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About This Item
Empirical Formula (Hill Notation):
C27H56NO7P
CAS Number:
Molecular Weight:
537.71
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
19:0 Lyso PC, Avanti Research™ - A Croda Brand 855776C
Assay
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (855776C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 855776C
concentration
10 mg/mL (855776C-25mg)
shipped in
dry ice
storage temp.
−20°C
General description
Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head.
Application
19:0 Lyso PC has been used for the quantification of lysophosphatidylcholine (LPC) in microsomes by mass spectrometry. It has also been used for plasma lipidome analysis of cows.
Biochem/physiol Actions
Lysophosphatidylcholine (LPC) modifies various biological functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC stimulates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.
Packaging
5 mL Clear Glass Sealed Ampule (855776C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
危险化学品
易制毒化学品（2类）
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Architecture of lipid droplets in endoplasmic reticulum is determined by phospholipid intrinsic curvature
Choudhary V, et al.
Current Biology, 28(6), 915-926 (2018)
Ruichuan Yin et al.
Nature protocols, 14(12), 3445-3470 (2019-11-15)
Mass spectrometry imaging (MSI) enables label-free spatial mapping of hundreds of biomolecules in tissue sections. This capability provides valuable information on tissue heterogeneity that is difficult to obtain using population-averaged assays. Despite substantial developments in both instrumentation and methodology, MSI
Altered plasma lipidome profile of dairy cows with fatty liver disease
Gerspach C, et al.
Research in Veterinary Science, 110, 47-59 (2017)
Marco Custódio et al.
Scientific reports, 10(1), 6583-6583 (2020-04-22)
Halophytes are increasingly regarded as suitable extractive species and co-products for coastal Integrated Multi-Trophic Aquaculture (IMTA) and studying their lipidome is a valid means towards their economic valorization. Halimione portulacoides (L.) Aellen edible leaves are rich in functional lipids with
Sidra Iqbal et al.
Plant physiology and biochemistry : PPB, 147, 101-112 (2019-12-20)
Plant phospholipase A (PLA) and C (PLC) families are least explored in terms of structure, diversity and their roles in membrane lipid remodeling under stress conditions. In this study, we performed gene family analysis, determined gene expression in different tissues
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