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About This Item
Empirical Formula (Hill Notation):
C22H46NO6PS
CAS Number:
Molecular Weight:
483.64
UNSPSC Code:
51191904
NACRES:
NA.28
SMILES string
[NH4+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)([O-])=S)OC
assay
≥99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (857235P-25MG), pkg of 1 × 5 mg (857235P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
shipped in
dry ice
storage temp.
−20°C
Application
lipids research
Packaging
5 mL Amber Glass Screw Cap Vial (857235P-5MG);
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
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Yutaka Hasegawa et al.
The Journal of biological chemistry, 278(14), 11962-11969 (2003-01-30)
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid mediator that acts through G protein-coupled receptors. Most cell lines in culture express one or more LPA receptors, making it difficult to assign a response to specific LPA receptors. Dissection of the signaling
Lian Qian et al.
Journal of medicinal chemistry, 46(26), 5575-5578 (2003-12-12)
The metabolically stabilized LPA analogue, 1-oleoyl-2-O-methyl-rac-glycerophosphothioate (OMPT), is a potent agonist for the LPA(3) G-protein-coupled receptor. A new enantiospecific synthesis of both (2R)-OMPT and (2S)-OMPT is described. Calcium release assays in both LPA(3)-transfected insect Sf9 and rat hepatoma Rh7777 cells
Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.
Hasegawa Y, et al.
The Journal of Biological Chemistry, 278, 11962-11969 (2003)
Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells
Brusevold IJ, et al.
BMC Cancer, 14(1), 432-432 (2014)
Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid
Motiejunaite R, et al.
Microvascular Research, 93(2), 62-71 (2014)
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