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About This Item
Empirical Formula (Hill Notation):
C41H80NO8P
CAS Number:
Molecular Weight:
746.05
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
16:0-17:0 cyclo PC, Avanti Research™ - A Croda Brand 857501P, powder
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (857501P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857501P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI key
MHMMFIIAMURXQM-DFCGPKRUSA-N
General description
16:0-17:0 cyclo PC or 1-palmitoyl-2-cis-9,10-methylenehexadecanoyl-sn-glycero-3-phosphocholine is a cyclopropane modified analog of PC. It is a glycerophospholipid and is the most important constituent of the eukaryotic cell membrane. Generally, it constitutes up to 40-50% of the cells and organelles.
Biochem/physiol Actions
Phosphatidylcholine (PC) is crucial for the synthesis of second messengers and lipid mediators. It also acts as an intermediate for the synthesis of other glycerophospholipid classes along with phosphatidylethanolamine (PE). Any disturbance in PC levels leads to various metabolic disorders.
Packaging
5 mL Amber Glass Screw Cap Vial (857501P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
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Selma Maric et al.
Applied microbiology and biotechnology, 99(1), 241-254 (2014-10-11)
Phosphatidylcholine (PC) is a major component of eukaryotic cell membranes and one of the most commonly used phospholipids for reconstitution of membrane proteins into carrier systems such as lipid vesicles, micelles and nanodiscs. Selectively deuterated versions of this lipid have
Lian Shan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 864(1-2), 22-28 (2008-02-12)
Lysophosphatidic acid (LPA) is a class of lipids that play multiple biological functions. Several reports show that they are potential biomarkers for diagnosing ovarian cancer. Therefore, it is necessary to accurately quantify their levels in biological samples. Here we report
Nicholas C Zitomer et al.
The Journal of biological chemistry, 284(8), 4786-4795 (2008-12-20)
Fumonisin B(1) (FB(1)) is a mycotoxin that inhibits ceramide synthases (CerS) and causes kidney and liver toxicity and other disease. Inhibition of CerS by FB(1) increases sphinganine (Sa), Sa 1-phosphate, and a previously unidentified metabolite. Analysis of the latter by
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent
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