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870013C

Avanti

16:0 MPB PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C51H84N2O11PNa
CAS Number:
384835-50-1
Molecular Weight:
955.18
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

16:0 MPB PE, Avanti Research™ - A Croda Brand 870013C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (870013C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870013C

concentration

10 mg/mL (870013C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCCC(C=C1)=CC=C1N(C(C=C2)=O)C2=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C51H85N2O11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-32-50(57)61-42-46(64-51(58)33-28-26-24-22-20-18-16-14-12-10-8-6-4-2)43-63-65(59,60)62-41-40-52-47(54)31-29-30-44-34-36-45(37-35-44)53-48(55)38-39-49(53)56;/h34-39,46H,3-33,40-43H2,1-2H3,(H,52,54)(H,59,60);/q;+1/p-1/t46-;/m1./s1

InChI key

REKODAHLWDSEBQ-FYQWNKFKSA-M

General description

Maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) also known as, DPPE-maleimide contains maleimide, which is a thiol-reactive moiety and a good electrophile. MPB PE is implicated in liposome preparation.

Application

16:0 maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) is suitable for use in preparation of liposomes by the film hydration technique.
16:0 MPB PE has been used:
  • for covalent coupling of monoclonal antibody
  • in the lipidation of C-terminal cysteine thiol of ligand binding site-1 (LBS-1)
  • to conjugate with peptides for incorporation into liposomes, which were then used in the surface plasmon resonance (SPR)-based binding experiments

Packaging

5 mL Clear Glass Sealed Ampule (870013C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Computed tomography in color: NanoK-enhanced spectral CT molecular imaging
Pan D, et al.
Angewandte Chemie (International ed. in English), 49(50), 9635-9639 (2010)
Stabilization of liposomes through enzymatic polymerization of DNA
Ruysschaert T, et al.
Nano Letters, 6(12), 2755-2757 (2006)
Liposomes as tools in basic research and industry (1994)
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