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Merck
CN

870436P

Avanti

C16:0 anandamide phosphate

Avanti Research™ - A Croda Brand

Synonym(s):

palmitoyl ethanolamide phosphate (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C18H37NO5PNa
Molecular Weight:
401.45
UNSPSC Code:
12352211
NACRES:
NA.25

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Product Name

C16:0 anandamide phosphate, Avanti Research™ - A Croda Brand 870436P, powder

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (870436P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870436P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCCCCCCCCCCCCCC)NCCOP(O)([O-])=O.[Na+]

General description

C16:0 anandamide is fatty acid amide, endogenic in nature. It is a member of the N-acylethanolamines family. Palmitoyl ethanolamide is present in egg yolk and peanut.
C16:0 anandamide phosphate is a phosphate ester of C16:0 anandamide. C16:0 anandamide, also known as N-palmitoyl ethanolamide, is a N-acyl ethanolamide derivative of palmitic acid.

Biochem/physiol Actions

Anandamide is a ligand for cannabinoid receptors. Anandamide possesses anti-inflammatory and pain killing action. It is effective in relieving pain associated with nerve compression syndrome and pudendal neuralgia. Anandamide is also useful in treating atopic eczema. Its effect is mediated by cannabinoid CB1 and CB2 receptors.
C16:0 anandamide or palmitoyl ethanolamide exhibits anti-inflammatory and analgesic properties. It is currently used as a veterinary anti-inflammatory agent.

Packaging

5 mL Amber Glass Screw Cap Vial (870436P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Flash Point(F)

No data available

Flash Point(C)

No data available

Regulatory Information

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Palmitoylethanolamide ameliorates carbon tetrachloride-induced liver fibrosis in rats
Ohara M, et al.
Frontiers in Pharmacology, 9, 698-711 (2018)
Ocular hypotensive effect of oral palmitoyl-ethanolamide: a clinical trial
Gagliano C, et al.
Investigative Ophthalmology & Visual Science, 52(9), 6096-6100 (2011)
Protective role of palmitoylethanolamide in contact allergic dermatitis
Petrosino S, et al.
Allergy, 65(6), 698-711 (2010)
Daria Vinokurova et al.
Frontiers in pharmacology, 9, 698-698 (2018-07-19)
Epipial application is one of the approaches for drug delivery into the cortex. However, passive diffusion of epipially applied drugs through the cortical depth may be slow, and different drug concentrations may be achieved at different rates across the cortical
Anandamide receptors
Di Marzo V, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 66(2-3), 377-391 (2002)
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