Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
oxPAPC, Avanti Research™ - A Croda Brand 870604P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 500 μg (870604P-500ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870604P
lipid type
phosphoglycerides
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is a mixture of oxidized phospholipid and a bioactive constituent of oxidized low-density lipoproteins (LDLs).
Application
Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is suitable for use to stimulate murine alveolar macrophages in vitro. It is also suitable for use to study its effects on human aortic endothelial cell metabolic reprogramming.
Biochem/physiol Actions
Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) show barrier-protective effects on human pulmonary endothelial monolayers. This lipid induce endothelial dysfunction by stimulating both pro- and anti-inflammatory pathways. OxPAPC is highly accumulated in atherosclerotic lesions and other sites of chronic inflammation.
Packaging
5 mL Clear Glass Sealed Ampule (870604P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
Birukov KG, et al.
Microvascular Research, 67(1), 18-28 (2004)
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC
Li R, et al.
Circulation Research, 98(5), 642-650 (2006)
Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury
Dubey PK, et al.
International Immunology, 29(2), 79-85 (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 870604P-500UG | 04061835353804 |