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About This Item
Empirical Formula (Hill Notation):
C22H45 N3O3
CAS Number:
Molecular Weight:
399.61
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
ST1326, Avanti Research™ - A Croda Brand 870853P, powder
SMILES string
[O-]C(C[C@@H](NC(NCCCCCCCCCCCCCC)=O)C[N+](C)(C)C)=O
InChI
1S/C22H45N3O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-22(28)24-20(18-21(26)27)19-25(2,3)4/h20H,5-19H2,1-4H3,(H2-,23,24,26,27,28)
InChI key
BMZYTDRMCBZVNH-UHFFFAOYSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (870853P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870853P
lipid type
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
General description
ST1326 contains an aliphatic carbon chain and is structurally similar to palmitoylcarnitine.
Biochem/physiol Actions
ST1326 is a reversible inhibitor of carnitine palmitoyltransferases. It shows anti tumor action in leukemia cell lines.
Packaging
5 mL Amber Glass Screw Cap Vial (870853P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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The carnitine system and cancer metabolic plasticity
Beatrice MMA, et al.
Cell Death & Disease, 9(2), 228-228 (2018)
A brain-liver circuit regulates glucose homeostasis
Pocai A, et al.
Cell Metabolism, 1(1), 53-61 (2005)
Structural insight into function and regulation of carnitine palmitoyltransferase
Rufer AC, et al.
Cellular and Molecular Life Sciences, 66(15), 2489-2501 (2009)
Ida Sofie Grønningsæter et al.
Cells, 9(5) (2020-05-13)
Acute myeloid leukemia (AML) is an aggressive blood cancer resulting in accumulation of immature, dysfunctional blood cells in the bone marrow. Changes in cell metabolism are features of many cancers, including AML and this may be exploited as a therapeutic
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