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About This Item
Empirical Formula (Hill Notation):
C28H58NO7P
CAS Number:
Molecular Weight:
551.74
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
C16-04:0 PC, Avanti Research™ - A Croda Brand 878115C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (878115C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 878115C
concentration
5 mg/mL (878115C-5mg)
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O
General description
C16-04:0 PC, also known as 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine (butanoyl-PAF), is a platelet-activating factor (PAF) analog. It is synthesized non-enzymatically in the oxidized-low density lipoprotein (Ox-LDL) particles. Butanoyl-PAF is mainly produced in the body during high oxidative stress. This lipid mediator exhibits pro-inflammatory activity.
Application
C16-04:0 PC or 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine may be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.
Packaging
5 mL Clear Glass Sealed Ampule (878115C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
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Sunil A Nankar et al.
Biochimie, 95(6), 1196-1207 (2013-02-05)
Apolipoprotein-derived peptides are promising candidates for the treatment of various inflammatory conditions and the main mechanism proposed for the protective action of these peptides includes binding to pro-inflammatory lipid mediators with high affinity and facilitating their sequestration/metabolism/clearance in the body.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 878115C-5MG | 04061838170101 |