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880160C

Avanti

16:0 PEG2000 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
474922-84-4
UNSPSC Code:
12352211
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Product Name

16:0 PEG2000 PE, Avanti Research™ - A Croda Brand 880160C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (880160C-25mg), pkg of 2 × 4 mL (880160C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880160C

concentration

10 mg/mL (880160C-25mg), 25 mg/mL (880160C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

16:0 PEG2000 PE, also called as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DPPEmPEG2000), is a polyethylene glycol (PEG)-modified lipid. Insertion of polyethylene glycol (PEG)-modified lipid to lipid- bilayer helps in formation of sterically stabilized liposome (SSL), which have an ability to spontaneously deliver drug to targeted cells.

Application

16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been to reduce the adhesion strength between the membrane and the glass during adhesion of cytoskeletal vesicles under hypertonic osmotic stress.

Packaging

5 mL Clear Glass Sealed Ampule (880160C-200mg)
5 mL Clear Glass Sealed Ampule (880160C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品

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Renu Maan et al.
Biophysical journal, 115(12), 2395-2402 (2018-11-21)
Regulation of adhesion is a ubiquitous feature of living cells, observed during processes such as motility, antigen recognition, or rigidity sensing. At the molecular scale, a myriad of mechanisms are necessary to recruit and activate the essential proteins, whereas at
Ilaria Arduino et al.
International journal of pharmaceutics, 583, 119351-119351 (2020-04-28)
Here, polyethylene glycol (PEG)-stabilized solid lipid nanoparticles (SLNs) containing Pt(IV) prodrugs derived from kiteplatin were designed and proposed as novel nanoformulations potentially useful for the treatment of glioblastoma multiforme. Four different Pt(IV) prodrugs were synthesized, starting from kiteplatin by the
D Kirpotin et al.
FEBS letters, 388(2-3), 115-118 (1996-06-17)
Plasma-stable liposomes (100 nm) were prepared from dioleoylphosphatidylethanolamine (DOPE) and 3-6 mol% of a new disulfide-linked poly(ethylene glycol)-phospholipid conjugate (mPEG-DTP-DSPE). In contrast to similar preparations containing non-cleavable PEG-phospholipid conjugate, thiolytic cleavage of the grafted polymer chains facilitated rapid and complete
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Global Trade Item Number

SKUGTIN
880160C-25MG04061837668401