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Merck
CN

880224C

Avanti

DSPE-PEG(5000) Maleimide

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] (ammonium salt)

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About This Item

CAS Number:
474922-22-0
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

DSPE-PEG(5000) Maleimide, Avanti Research™ - A Croda Brand 880224C

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (880224C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880224C

concentration

5 mg/mL (880224C-5mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCCCCCCCCCCCCCCCC)OC[C@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP([O-])(OCCNC([(OCH2CH2)113]NC(CCN1C(C=CC1=O)=O)=O)=O)=O.[NH4+]

General description

DSPE-PEG(5000) Maleimide, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000], is a functionalized polyethylene glycol (PEG) lipid.

Application

DSPE-PEG(5000) Maleimide or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] has been used in conjugation with asparagine-glycine-arginine peptide (NGR) molecule to prepare DSPE-PEG5000-NGR lipososmes.

Packaging

5 mL Clear Glass Sealed Ampule (880224C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

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Yang Yang et al.
Biomaterials, 48, 84-96 (2015-02-24)
Tumor-oriented nanocarrier drug delivery approaches with photosensitivity have drawn considerable attention over the years. However, due to its low penetrability and ability to harm tissues, the use of UV light for triggered nanocarrier release in in vivo applications has been

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