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Merck
CN

880258P

Avanti

C18:0 DG-PEG2K-triGalNAc

Avanti Research - A Croda Brand

Synonym(s):

C18:0 DG-PEG2K-triGalNAc, 1,2-Dioctadecyl-sn-glycero-3N-[carboxy(polyethylene glycol)-2000]-N-tri(N-acetylgalactosamine)

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About This Item

Empirical Formula (Hill Notation):
C181H351N9O75
CAS Number:
Molecular Weight:
3853.74
UNSPSC Code:
12352211
NACRES:
NA.21
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biological source

synthetic

assay

> 99%

form

powder

packaging

pkg of 1 × 5 mg 880258P-5MG

manufacturer/tradename

Avanti Research - A Croda Brand

solubility

water: soluble at 20 °C

lipid type

polymerizable lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCCCCCCCCCCCOC[C@H](CNC(=O)COCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO[O](=O)\C=C\CC(=O)NCCCCC(N(CC(=O)NCCOCCOCCOC1OC(CO)C(O)C(O)C1NC(C)=O)CC(=O)NCCOCCOCCOC1OC(CO)C(O)C(O)C1NC(C)=O)C(=O)NCCOCCOCCOC1OC(CO)C(O)C(O)C1NC(C)=O)OCCCCCCCCCCCCCCCCCC

General description

C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that enhances targeted drug delivery by binding to the Asialoglycoprotein Receptor (ASGPR) which are predominantly found on the surface of liver cells.

Application

Targeted Drug Delivery

Features and Benefits

Functionalizing C18:0 DG-PEG2K with triGalNac allows this to be used in the formation of liposomes or LNPs that target the liver for drug delivery.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
880258P-5MG04065273291261