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Merck
CN

880347P

Avanti

14:0-14:0(COOH) PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-myristoyl-2-(14-carboxymyristoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C36H70NO10P
CAS Number:
119766-79-9
Molecular Weight:
707.92
MDL number:
MFCD22416949
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

14:0-14:0(COOH) PC, Avanti Research™ - A Croda Brand 880347P, powder

InChI

1S/C36H70NO10P/c1-5-6-7-8-9-10-11-15-18-21-24-27-35(40)44-31-33(32-46-48(42,43)45-30-29-37(2,3)4)47-36(41)28-25-22-19-16-13-12-14-17-20-23-26-34(38)39/h33H,5-32H2,1-4H3,(H-,38,39,42,43)/t33-/m1/s1

InChI key

LEUFNPCYKIWNSX-MGBGTMOVSA-N

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC(O)=O)=O)COC(CCCCCCCCCCCCC)=O)=O

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 mg (880347P-100mg)
pkg of 1 × 25 mg (880347P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880347P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

14:0-14:0(COOH) PC is suitable for use in the synthesis of phospholipid-nonaarginine conjugates (PL9R).

Biochem/physiol Actions

14:0-14:0(COOH) PC can be used to form well organized and stable phospholipid self-assembled monolayers (SAMs) by covalently attaching to silica substrates.

Packaging

5 mL Clear Glass Sealed Ampule (880347P-100mg)
5 mL Clear Glass Sealed Ampule (880347P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

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Ji Hee Kang et al.
Biomacromolecules, 18(11), 3733-3741 (2017-09-28)
Despite potential applications of nucleic acid therapeutics, the lack of effective delivery systems hinders their clinical application. To overcome the barriers to nucleic acid delivery, we previously reported nanoparticles using phospholipid-polyethylenimine conjugates. However, toxicity of polyethylenimine remains as a problematic
Biomembrane mimetic surfaces by phospholipid self-assembled monolayers on silica substrates
Yang Z and Yu H
Langmuir, 15(5), 1731-1737 (1999)
Patrick Drücker et al.
Langmuir : the ACS journal of surfaces and colloids, 30(49), 14877-14886 (2014-11-22)
Solid-supported lipid bilayers (SLBs) mimicking a biological membrane are commonly used to investigate lipid-lipid or lipid-protein interactions. Simple binary or ternary lipid systems are well established, whereas more complex model membranes containing biologically important signaling lipids such as phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2)

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