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880410C

Avanti

14:0 PEG350 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)

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About This Item

CAS Number:
474922-82-2
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

14:0 PEG350 PE, Avanti Research™ - A Croda Brand 880410C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (880410C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880410C

concentration

10 mg/mL (880410C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

General description

14:0 PEG350 PE is a polyethylene glycol (PEG) conjugated phospholipid. PEGylated phospholipids are amphiphilic polymers.
Poly (ethylene glycol)s (PEGs)- phosphatidylethanolamines (PEs) lipids are anionic double tailed lipids. Its structure contains a wedge shaped bulky hydrophilic polar head.

Application

14:0 PEG350 PE is suitable for use in the preparation of floating bilayer lipid membrane to mimic the environment of a biological cell membrane.

Biochem/physiol Actions

Liposome formulation commonly incorporates polyethylene glycol (PEG) conjugated phospholipids, as they efficiently maintain their stereochemistry. They are also used as drug carriers. The formation of mixed micelles is supported by the use of highly concentrated PEG-lipids.
Poly (ethylene glycol)s (PEGs)- phosphatidylethanolamines (PEs) lipids are key constituents of sterically stabilized liposomes, which are used as drug vehicles.

Packaging

5 mL Clear Glass Sealed Ampule (880410C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Rosa Bartucci et al.
Chemistry and physics of lipids, 124(2), 111-122 (2003-06-24)
Conventional electron spin resonance (ESR) spectroscopy of different positional isomers of phosphatidylcholine spin labels (n-PCSL; n=5, 7, 10, 12, 14, and 16) has been used to study micellar dispersions made of poly(ethylene glycol)s-phosphatidylethanolamines (PEGs-PEs) polymer-lipids. Such aggregates are currently used
Micro- and Nanoengineering of the Cell Surface (2014)
Electrochemical and PM-IRRAS studies of floating lipid bilayers assembled at the Au (111) electrode pre-modified with a hydrophilic monolayer
Su Z, et al.
Journal of Electroanalytical Chemistry, 688, 76-85 (2013)
View All Related Papers

Global Trade Item Number

SKUGTIN
880410C-25MG04061837668593