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880510P

Avanti

14:0 PEG550 PE

Avanti Polar Lipids 880510P, powder

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Synonym(s):
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt)
CAS Number:
474922-82-2
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (880510P-25mg)

manufacturer/tradename

Avanti Polar Lipids 880510P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

General description

14:0 PEG550 PE is a synthetic anionic lipid. It contains 14-carbon acyl chains conjugated to phosphoethanolamine headgroup and polyethylene-glycol. The molecular weight and exact mass are averages based on the polydispersity of PEG.

Application

14:0 PEG550 PE might be used as lipid additive to study its effect on the phase properties of hydrated monoolein. It is also suitable for use in the formation of liposomes encapsulating hemoglobin (LEHs).

Biochem/physiol Actions

14:0 PEG550 PE is applicable in targeted drug delivery. It favors the formation of hexagonal (HI)-phase lipids.

Packaging

5 mL Clear Glass Sealed Ampule (880510P-25mg)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Dian R Arifin et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 33(2), 137-162 (2005-06-18)
Liposomes encapsulating hemoglobin (LEHs) surface-conjugated with 2000 and 550 Da poly(ethylene glycol) (PEG) were produced via extrusion through 400, 200 and 100 nm pore diameter membranes in two types of phosphate buffer with different ionic strengths. The lipid bilayers were
Vadim Cherezov et al.
Biophysical journal, 83(6), 3393-3407 (2002-12-24)
Hydrated monoolein forms the cubic-Pn3m mesophase that has been used for in meso crystallization of membrane proteins. The crystals have subsequently provided high-resolution structures by crystallographic means. It is possible that the hosting cubic phase created by monoolein alone, which
Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and

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