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Merck
CN

880520P

Avanti

18:0 PEG550 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt)

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About This Item

CAS Number:
474922-77-5
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

18:0 PEG550 PE, Avanti Research™ - A Croda Brand 880520P, powder

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (880520P-200mg)
pkg of 1 × 25 mg (880520P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880520P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C67H132NO22P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-65(69)87-62-64(90-66(70)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)63-89-91(72,73)88-37-36-68-67(71)86-61-60-85-59-58-84-57-56-83-55-54-82-53-52-81-51-50-80-49-48-79-47-46-78-45-44-77

InChI key

BVFRHFBILZSLAT-DBYYOURKSA-N

General description

18:0 PEG550 PE is polymer grafted lipid. The molecular weight and exact mass are averages based on the polydispersity of polyethylene glycol (PEG).

Application

18:0 PEG550 PE is suitable for the preparation of 5(6)-carboxyfluorescein-containing PEGylated liposomes (CFL-PEGs) and sensor fabrication. It is also suitable in the preparation of giant vesicles to study its effect on the vesicle properties.

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol (DSPE-PEG) favors micelles formation due to a large hydrophilic head group. The portion of micelles is greater in the pure and polymer conjugated lipid mixture, when the latter concentration is more. The vesicle-to-micelle transition is also affected by the molecular weight of the conjugated polymer.

Packaging

20 mL Clear Glass Screw Cap Vial (880520P-200mg)
5 mL Clear Glass Sealed Ampule (880520P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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J Matthew Dubach et al.
Integrative biology : quantitative biosciences from nano to macro, 3(2), 142-148 (2010-11-23)
Sodium balance is vital to maintaining normal physiological function. Imbalances can occur in a variety of diseases, during certain surgical operations or during rigorous exercise. There is currently no method to continuously monitor sodium concentration in patients who may be
Amit Mahendra et al.
Chemistry and physics of lipids, 218, 47-56 (2018-12-07)
Incorporation of low molecular weight poly-ethylene glycol (PEG) - grafted phospholipids in vesicle bilayers is known to increase the circulation time of liposomal drug delivery vehicles. Mechanical properties of giant unilamellar DPPC vesicles containing varying concentrations of DSPE-PEG (PEG MW:
Tetsuya Fujie et al.
Soft matter, 15(46), 9537-9546 (2019-11-13)
Liposomes are applicable to fabrication of colloidal carriers of drugs and proteins. Physicochemical stimuli-triggered leakage from liposomes offers a wide variety of applications in biochemical and biomedical fields. In this work, effects of bubbles on the characteristics of PEGylated liposomes
Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and

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