Product Name
18:0 PEG750 PE, Avanti Research™ - A Croda Brand 880620P, powder
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (880620P-200mg)
pkg of 1 × 25 mg (880620P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880620P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]
InChI key
QAVSYMFTABOITA-CQZUBJGASA-N
General description
18:0 PEG750 PE is a polyethylene glycol (PEG) conjugated phospholipid. The molecular weight and exact mass are averages based on the polydispersity of PEG.
Application
18:0 PEG750 PE might be used to PEGylate lipoplexes and to study the feasibility of its entrapment into a solid matrix system for prolonged delivery of siRNA in vaginal mucus.
Biochem/physiol Actions
18:0 PEG750 PE is useful as a micelle-forming component.
Packaging
20 mL Clear Glass Screw Cap Vial (880620P-200mg)
5 mL Clear Glass Sealed Ampule (880620P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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Tania Furst et al.
Journal of controlled release : official journal of the Controlled Release Society, 236, 68-78 (2016-06-23)
Topical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a prolonged delivery and
Rupa R Sawant et al.
International journal of pharmaceutics, 374(1-2), 114-118 (2009-05-19)
Cell-penetrating peptide (TATp) was attached to the distal tips of polyethyleneglycol (PEG) moieties of polyethyleneglycol-phosphatidylethanolamine (PEG-PE) micelles loaded with paclitaxel (PCT). The TATp-modified micelles demonstrated an increased interaction with cancer cells compared to non-modified micelles resulting in a significant increase
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