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Merck
CN

890840C

Avanti

14:0 DAP

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dimyristoyl-3-dimethylammonium-propane

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About This Item

Empirical Formula (Hill Notation):
C33H65NO4
CAS Number:
72719-84-7
Molecular Weight:
539.87
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

14:0 DAP, Avanti Research™ - A Croda Brand 890840C

SMILES string

[H]C(CN(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890840C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 890840C

concentration

10 mg/mL (890840C-25mg)

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

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Application

1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) might be used:
  • to prepare liposomal membrane and to study its interaction between surfactants
  • to study its effect on the ordering of two-dimensional dispersions of membrane-coated particles
  • to study its interaction with mastoparan (MP)

Biochem/physiol Actions

1,2-dimyristoyl-3-dimethylammonium-propane (14:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.

Packaging

5 mL Clear Glass Sealed Ampule (890840C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Specific ion interaction dominates over hydrophobic matching effects in peptide-lipid bilayer interactions: the case of short peptide
Wei F, et al.
The Journal of Physical Chemistry C, 117(49), 26190-26196 (2013)
F Nomura et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(5), 2340-2345 (2001-02-28)
Dynamic behaviors of liposomes caused by interactions between liposomal membranes and surfactant were studied by direct real-time observation by using high-intensity dark-field microscopy. Solubilization of liposomes by surfactants is thought to be a catastrophic event akin to the explosion of
Esther W Gomez et al.
Soft matter, 5(9), 1931-1936 (2009-05-07)
Two-dimensional dispersions of colloidal particles with a range of surface chemistries and electrostatic potentials are characterized under a series of solution ionic strengths. A combination of optical imaging techniques are employed to monitor both the colloid structure and the electrostatic

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