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Merck
CN

999988C

Avanti

13:0 Diether PC

Avanti Research - A Croda Brand

Synonym(s):

1,2-di-O-tridecyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C34H72NO6P
CAS Number:
Molecular Weight:
621.91
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

13:0 Diether PC, Avanti Research - A Croda Brand 999988C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (999988C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 999988C

concentration

10 mg/mL (999988C-10mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCC)COCCCCCCCCCCCCC)=O

General description

13:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two tridecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Application

13:0 Diether PC or 1,2-di-O-tridecyl-sn-glycero-3-phosphocholine is suitable for bicelle preparation and as an internal standard for lipid identification in tissue.

Biochem/physiol Actions

13:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Clear Glass Sealed Ampule (999988C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Certificates of Analysis (COA)

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Hugo F Azurmendi et al.
Carbohydrate research, 337(10), 905-915 (2002-05-15)
The conformations of two synthetic trisaccharides of blood group A and B (alpha-L-Fucp-(1-->2)-[alpha-D-GalpNAc-(1-->3)]-alpha-D-Galp and alpha-L-Fucp-(1-->2)-[alpha-D-Galp-(1-->3)]-alpha-D-Galp, respectively) and of a type A tetrasaccharide alditol, Fucp-(1-->2)-[alpha-D-GalpNAc-(1-->3)]-beta-D-Galp-(1-->3)-GalNAc-ol, were studied by NMR measurements of one-bond C-H residual dipolar couplings in partially oriented liquid crystal
Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
Baumeier C, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1851(5), 566-576 (2015)
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This



Global Trade Item Number

SKUGTIN
999988C-10MG04061837793776