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Merck
CN

LM4000

Avanti

19:0 Cholesterol ester

Avanti Research™ - A Croda Brand

Synonym(s):

cholest-5-en-3β-yl nonadecanoate

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About This Item

Empirical Formula (Hill Notation):
C46H82O2
CAS Number:
25605-90-7
Molecular Weight:
667.14
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

19:0 Cholesterol ester, Avanti Research™ - A Croda Brand LM4000, (methanol/chloroform/toluene (50:25:25) solution)

InChI key

VHYWECIJXTVRSG-TVDLSCFRSA-N

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](OC(CCCCCCCCCCCCCCCCCC)=O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

form

(methanol/chloroform/toluene (50:25:25) solution)

packaging

pkg of 1 × 1 mL (LM4000-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM4000

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

General description

19:0 Cholesterol ester is the central core of lipoprotein particles. CE formation is catalyzed by the enzyme lecithin cholesterol acyl transferase (LCAT).

Application

19:0 Cholesterol ester has been used as a quantitative lipid standard to monitor different lipid extract concentrations.

Biochem/physiol Actions

CE hydrolysis mediates reverse cholesterol transport in macrophage foam cells.

Packaging

2 mL Amber Glass Sealed Ampule (LM4000-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT RE 2 - STOT SE 1 - STOT SE 3

target_organs

Central nervous system, Eyes, Liver,Kidney

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品
易制毒化学品（2类）
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Mammalian acyl-CoA:cholesterol acyltransferases
Buhman KF, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1529(1), 142-154 (2000)
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages.
Igarashi M, et al.
Circulation Research, 107(11), 1387-1395 (2010)
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)

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