N-079
(R,S)-Norcotinine solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
Molecular Weight:
162.19
UNSPSC Code:
41116107
PubChem Substance ID:
MDL number:
grade
certified reference material
Quality Level
feature
(Snap-N-Spike®)
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
format
single component solution
storage temp.
−20°C
SMILES string
O=C1NC(C2=CN=CC=C2)CC1
InChI
1S/C9H10N2O/c12-9-4-3-8(11-9)7-2-1-5-10-6-7/h1-2,5-6,8H,3-4H2,(H,11,12)
InChI key
FXFANIORDKRCCA-UHFFFAOYSA-N
General description
Norcotinine, or desmethylcotinine, is a urinary metabolite of nornicotine and cotinine found in smokers and users of other nicotine products including chewing tobacco and snuff. This Certified Spiking Solution® is suitable for use in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers by LC-MS/MS or GC/MS.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
49.5 °F
flash_point_c
9.7 °C
Regulatory Information
危险化学品
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Janne Hukkanen et al.
Clinical pharmacology and therapeutics, 80(5), 522-530 (2006-11-23)
Grapefruit juice is an inhibitor of the cytochrome P450 (CYP) 3A4 enzyme and transporters such as P-glycoprotein and organic anion transporting polypeptides, leading to clinically important interactions. Our objective was to study the effect of grapefruit juice on the pharmacokinetics
Liza U Ljungberg et al.
Endothelium : journal of endothelial cell research, 15(5-6), 239-245 (2008-12-10)
Nicotine has been shown to induce endothelial dysfunction, which is an early marker of atherosclerosis. Nicotine undergoes extensive metabolism in the liver, forming a number of major and minor metabolites. There are very limited data on the effect of nicotine
Diaa M Shakleya et al.
Analytical and bioanalytical chemistry, 395(7), 2349-2357 (2009-10-20)
An analytical procedure was developed and validated for the simultaneous identification and quantification of nicotine, cotinine, trans-3'-hydroxycotinine, and norcotinine in 0.5 mL of human oral fluid collected with the Quantisal oral fluid collection device. Solid phase extraction and liquid chromatography-tandem