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Merck
CN

A-040

Supelco

Aminorex solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
2207-50-3
Molecular Weight:
162.19
UNSPSC Code:
41116107

Key Documents

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grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
kontrollierte Droge in Deutschland

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

NC1=NCC(O1)c2ccccc2

InChI

1S/C9H10N2O/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)

InChI key

SYAKTDIEAPMBAL-UHFFFAOYSA-N

General description

An analytical reference standard suitable for use in LC/MS or GC/MS methods for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research applications. Aminorex is an anorectic stimulant drug and appetite suppressant marketed under the names Menocil and Apiquel®. The drug was retired from the market after it was found to cause pulmonary hypertension.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Apiquel is a registered trademark of Puricorp Holdings LLC
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Regulatory Information

监管及禁止进口产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Relearning the lessons of history: anorexigens and pulmonary hypertension.
D Langleben
Chest, 114(1 Suppl), 55S-57S (1998-07-24)
R M Tuder et al.
American journal of respiratory and critical care medicine, 158(6), 1999-2001 (1998-12-16)
Anorexigens such as aminorex fumarate and dexfenfluramine are associated with the development of severe pulmonary hypertension (PH), which clinically and histopathologically is considered indistinguishable from idiopathic or primary pulmonary hypertension (PPH). For the current study, we asked whether anorexigen-associated PH
Two different drug-induced pulmonary complications in a patient suffering from rheumatoid arthritis.
B F Leeb et al.
British journal of rheumatology, 37(5), 586-587 (1998-07-03)
Steven B Karch et al.
International journal of cardiology, 158(3), 344-346 (2011-07-19)
Levamisole is found in more than 80% of illicit cocaine seized within United States borders. Percentages are somewhat lower in Europe. In 2009, controlled in vivo studies demonstrated that horses metabolize levamisole to aminorex. Earlier this year our laboratory demonstrated
S B Gross et al.
Reviews in cardiovascular medicine, 1(2), 80-89 (2002-11-29)
Three years after the withdrawal of fenfluramine and dexfenfluramine from the market, the magnitude and prevalence of their deleterious cardiopulmonary effects remain undetermined. The links between these anorexigens and valvular heart disease and primary pulmonary hypertension, however, are clearly established.
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