A-134
Acetaminophen (Paracetamol) Impurity Mixture solution
25 μg/mL in methanol (each analyte), certified reference material, ampule of 1 mL, Cerilliant®
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About This Item
UNSPSC Code:
12352200
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
25 μg/mL in methanol (each analyte)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
pharmaceutical (small molecule)
format
multi-component solution
storage temp.
−20°C
General description
Acetaminophen is formed as a metabolic product of phenacetin and is a well-known drug used in the treatment of pain and fever due to its effective central analgesic and antipyretic properties. It is also the only analgesic drug that is non-opioid and available in the oral, rectal, and intravenous formulation forms. It has been posited to inhibit the synthesis of prostaglandins and exhibit a mode of action similar to nonsteroidal anti-inflammatory drugs (NSAIDs).
Application
Acetaminophen Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Analyte
Description
- Acetaminophen Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
- Acetaminophen Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material
- Acetaminophen Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material
- Acetaminophen Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material
- Acetaminophen, Pharmaceutical Secondary Standard; Certified Reference Material
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
Storage Class
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Regulatory Information
监管及禁止进口产品
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Intravenous paracetamol (acetaminophen)
Duggan ST and Scott LJ
Drugs, 69(1), 101- 113 (2009)
Acetaminophen poisoning and toxicity
Rumack BH and Matthew H
Pediatrics, 55(6), 871- 876 (1975)
Central analgesic effect of acetaminophen but not of aspirin
Piletta P, et al.
Clinical Pharmacology and Therapeutics, 49(4), 350- 354 (1991)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML0743-10MG | 04061837107030 |
| SML0743-50MG | 04061832723952 |
| 69152-5G-F | 04061833447970 |
| 69152-25G-F | 04061833365496 |
| 12122002-1VL | 04061837343667 |
| MAB80125 | 04053252668128 |
| MABF3046-100UL | 04065266060188 |
| MABF3046-25UL | 04065266060195 |
| SAB4504114-100UG | 04061831455311 |
| MAB16990 | 04053252576737 |
| HLTUD0199 | 04061836098148 |
| MSTUD0046 | 04061836858018 |
| MLTUD0045 | 04061836067700 |
| MLTUD0046 | 04061836067717 |
| MLMIR0046 | 04061836706777 |
| MLMIR0045 | 04061836706760 |
| HLMIR0199 | 04061836734282 |
| HLMIR2254 | 04061836730321 |
| Z214760-1EA | 04061832348780 |
| Z406686-1EA | 04061832349459 |
| Z508616-1EA | 04061832349992 |
| WHA10452006 | 04061831601084 |