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A-914

7-Aminonitrazepam solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O
CAS Number:
4928-02-3
Molecular Weight:
251.28
NACRES:
NA.24
PubChem Substance ID:
329771037
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
MFCD00800998
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grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing
pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

O=C1NC2=CC=C(N)C=C2C(C3=CC=CC=C3)=NC1

InChI

1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19)

InChI key

OYOUQHVDCKOOAL-UHFFFAOYSA-N

General description

7-Aminonitrazepam is a major urinary metabolite of nitrazepam, a benzodiazepine used to treat insomnia and sold under the trade names Mogadon and Alodorm. This certified solution standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug monitoring of nitrazepam use.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Regulatory Information

监管及禁止进口产品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yu Zhu et al.
Se pu = Chinese journal of chromatography, 20(5), 394-397 (2005-12-20)
A highly sensitive method has been developed for the analysis of 7-aminonitrazepam (7-ANIZ), the major metabolite of nitrazepam, in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry. Urine samples were extracted with ethyl ether-ethyl acetate (99:1, volume ratio). The extracts were derivatized
B J Hart et al.
Methods and findings in experimental and clinical pharmacology, 10(1), 21-26 (1988-01-01)
The stability of some selected benzodiazepines in saliva has been studied. The benzodiazepines nitrazepam and clonazepam were found to be unstable in saliva at room temperature and nitrazepam was converted into 7-aminonitrazepam. The conversion rate of nitrazepam was strongly dependent
High-performance liquid chromatographic determination of nitrazepam and its metabolites in human urine.
T Kozu
Journal of chromatography, 310(1), 213-218 (1984-09-14)
View All Related Papers

Global Trade Item Number

SKUGTIN
PH015305-1G04061825646336
CDS022231-25MG04061829028275
PH015123-100MG04061831271690
CDS021975-100MG04061829017880
CDS023040-25MG04061829010867
PH015396-1G04061825647135
460125-100ML04061837812590
GF52616875-1EA04061825096353
GF68647977-1EA04061825088365
GF47160738-1EA04061825095431
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